Kristin Sellers, PhD

Assistant Adjunct Professor
Neurological Surgery

Dr. Sellers is an Assistant Adjunct Professor in the Department of Neurological Surgery. She studies intracranial electrical stimulation for the treatment of neuropsychiatric disorders including major depressive disorder and chronic pain. She works to translate learnings from early stage clinical trials of closed-loop neuromodulation for the development of neurotechnologies and supporting infrastructure.

Publications: 

Large-scale single-neuron speech sound encoding across the depth of human cortex.

Nature

Leonard MK, Gwilliams L, Sellers KK, Chung JE, Xu D, Mischler G, Mesgarani N, Welkenhuysen M, Dutta B, Chang EF

DREDge: robust motion correction for high-density extracellular recordings across species.

bioRxiv : the preprint server for biology

Windolf C, Yu H, Paulk AC, Meszéna D, Muñoz W, Boussard J, Hardstone R, Caprara I, Jamali M, Kfir Y, Xu D, Chung JE, Sellers KK, Ye Z, Shaker J, Lebedeva A, Raghavan M, Trautmann E, Melin M, Couto J, Garcia S, Coughlin B, Horváth C, Fiáth R, Ulbert I, Movshon JA, Shadlen MN, Churchland MM, Churchland AK, Steinmetz NA, Chang EF, Schweitzer JS, Williams ZM, Cash SS, Paninski L, Varol E

Closed-Loop Neurostimulation for Biomarker-Driven, Personalized Treatment of Major Depressive Disorder.

Journal of visualized experiments : JoVE

Sellers KK, Khambhati AN, Stapper N, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD

Intracranial electrical stimulation of corticolimbic sites modulates arousal in humans.

Brain stimulation

Fan JM, Lee AM, Sellers KK, Woodworth K, Makhoul GS, Liu TX, Henderson C, Astudillo Maya DA, Martinez R, Zamanian H, Speidel BA, Khambhati AN, Rao VR, Sugrue LP, Scangos KW, Chang EF, Krystal AD

Closed-loop neurostimulation for the treatment of psychiatric disorders.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Sellers KK, Cohen JL, Khambhati AN, Fan JM, Lee AM, Chang EF, Krystal AD

Epileptiform discharges triggered with direct electrical stimulation for treatment-resistant depression: Factors that modulate risk and treatment considerations.

Brain stimulation

Fan JM, Khambhati AN, Sellers KK, Stapper N, Maya DA, Kunwar E, Henderson C, Sugrue LP, Scangos KW, Chang EF, Rao VR, Krystal AD

Changes in intracranial neurophysiology associated with acute COVID-19 infection.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

Sellers KK, Stapper N, Astudillo Maya DA, Henderson C, Khambhati AN, Fan JM, Rao VR, Scangos KW, Chang EF, Krystal AD

High-density single-unit human cortical recordings using the Neuropixels probe.

Neuron

Chung JE, Sellers KK, Leonard MK, Gwilliams L, Xu D, Dougherty ME, Kharazia V, Metzger SL, Welkenhuysen M, Dutta B, Chang EF

Practical Closed-Loop Strategies for Deep Brain Stimulation: Lessons From Chronic Pain.

Frontiers in neuroscience

Prosky J, Cagle J, Sellers KK, Gilron R, de Hemptinne C, Schmitgen A, Starr PA, Chang EF, Shirvalkar P

Closed-loop neuromodulation in an individual with treatment-resistant depression.

Nature medicine

Scangos KW, Khambhati AN, Daly PM, Makhoul GS, Sugrue LP, Zamanian H, Liu TX, Rao VR, Sellers KK, Dawes HE, Starr PA, Krystal AD, Chang EF

Thin-film microfabrication and intraoperative testing ofµECoG and iEEG depth arrays for sense and stimulation.

Journal of neural engineering

Sellers KK, Chung JE, Zhou J, Triplett MG, Dawes HE, Haque R, Chang EF

Analysis-rcs-data: Open-Source Toolbox for the Ingestion, Time-Alignment, and Visualization of Sense and Stimulation Data From the Medtronic Summit RC+S System.

Frontiers in human neuroscience

Sellers KK, Gilron R, Anso J, Louie KH, Shirvalkar PR, Chang EF, Little SJ, Starr PA

Bidirectional propagation of low frequency oscillations over the human hippocampal surface.

Nature communications

Kleen JK, Chung JE, Sellers KK, Zhou J, Triplett M, Lee K, Tooker A, Haque R, Chang EF

Rapid deployment of SARS-CoV-2 testing: The CLIAHUB.

PLoS pathogens

Crawford ED, Acosta I, Ahyong V, Anderson EC, Arevalo S, Asarnow D, Axelrod S, Ayscue P, Azimi CS, Azumaya CM, Bachl S, Bachmutsky I, Bhaduri A, Brown JB, Batson J, Behnert A, Boileau RM, Bollam SR, Bonny AR, Booth D, Borja MJB, Brown D, Buie B, Burnett CE, Byrnes LE, Cabral KA, Cabrera JP, Caldera S, Canales G, Castañeda GR, Chan AP, Chang CR, Charles-Orszag A, Cheung C, Chio U, Chow ED, Citron YR, Cohen A, Cohn LB, Chiu C, Cole MA, Conrad DN, Constantino A, Cote A, Crayton-Hall T, Darmanis S, Detweiler AM, Dial RL, Dong S, Duarte EM, Dynerman D, Egger R, Fanton A, Frumm SM, Fu BXH, Garcia VE, Garcia J, Gladkova C, Goldman M, Gomez-Sjoberg R, Gordon MG, Grove JCR, Gupta S, Haddjeri-Hopkins A, Hadley P, Haliburton J, Hao SL, Hartoularos G, Herrera N, Hilberg M, Ho KYE, Hoppe N, Hosseinzadeh S, Howard CJ, Hussmann JA, Hwang E, Ingebrigtsen D, Jackson JR, Jowhar ZM, Kain D, Kim JYS, Kistler A, Kreutzfeld O, Kulsuptrakul J, Kung AF, Langelier C, Laurie MT, Lee L, Leng K, Leon KE, Leonetti MD, Levan SR, Li S, Li AW, Liu J, Lubin HS, Lyden A, Mann J, Mann S, Margulis G, Marquez DM, Marsh BP, Martyn C, McCarthy EE, McGeever A, Merriman AF, Meyer LK, Miller S, Moore MK, Mowery CT, Mukhtar T, Mwakibete LL, Narez N, Neff NF, Osso LA, Oviedo D, Peng S, Phelps M, Phong K, Picard P, Pieper LM, Pincha N, Pisco AO, Pogson A, Pourmal S, Puccinelli RR, Puschnik AS, Rackaityte E, Raghavan P, Raghavan M, Reese J, Replogle JM, Retallack H, Reyes H, Rose D, Rosenberg MF, Sanchez-Guerrero E, Sattler SM, Savy L, See SK, Sellers KK, Serpa PH, Sheehy M, Sheu J, Silas S, Streithorst JA, Strickland J, Stryke D, Sunshine S, Suslow P, Sutanto R, Tamura S, Tan M, Tan J, Tang A, Tato CM, Taylor JC, Tenvooren I, Thompson EM, Thornborrow EC, Tse E, Tung T, Turner ML, Turner VS, Turnham RE, Turocy MJ, Vaidyanathan TV, Vainchtein ID, Vanaerschot M, Vazquez SE, Wandler AM, Wapniarski A, Webber JT, Weinberg ZY, Westbrook A, Wong AW, Wong E, Worthington G, Xie F, Xu A, Yamamoto T, Yang Y, Yarza F, Zaltsman Y, Zheng T, DeRisi JL

A Deep Brain Stimulation Trial Period for Treating Chronic Pain.

Journal of clinical medicine

Shirvalkar P, Sellers KK, Schmitgen A, Prosky J, Joseph I, Starr PA, Chang EF

Pilot Study of An Intracranial Electroencephalography Biomarker of Depressive Symptoms in Epilepsy.

The Journal of neuropsychiatry and clinical neurosciences

Scangos KW, Ahmad HS, Shafi A, Sellers KK, Dawes HE, Krystal A, Chang EF

Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression.

Current biology : CB

Rao VR, Sellers KK, Wallace DL, Lee MB, Bijanzadeh M, Sani OG, Yang Y, Shanechi MM, Dawes HE, Chang EF

Early Development of Network Oscillations in the Ferret Visual Cortex.

Scientific reports

Li Y, Yu C, Zhou ZC, Stitt I, Sellers KK, Gilmore JH, Frohlich F

Breakdown of local information processing may underlie isoflurane anesthesia effects.

PLoS computational biology

Wollstadt P, Sellers KK, Rudelt L, Priesemann V, Hutt A, Fröhlich F, Wibral M

Oscillatory Dynamics in the Frontoparietal Attention Network during Sustained Attention in the Ferret.

Cell reports

Sellers KK, Yu C, Zhou ZC, Stitt I, Li Y, Radtke-Schuller S, Alagapan S, Fröhlich F

Resting state network topology of the ferret brain.

NeuroImage

Zhou ZC, Salzwedel AP, Radtke-Schuller S, Li Y, Sellers KK, Gilmore JH, Shih YY, Fröhlich F, Gao W

Statistical Frequency-Dependent Analysis of Trial-to-Trial Variability in Single Time Series by Recurrence Plots.

Frontiers in systems neuroscience

Tošic T, Sellers KK, Fröhlich F, Fedotenkova M, Beim Graben P, Hutt A

Structural and functional connectivity between the lateral posterior-pulvinar complex and primary visual cortex in the ferret.

The European journal of neuroscience

Yu C, Sellers KK, Radtke-Schuller S, Lu J, Xing L, Ghukasyan V, Li Y, Shih YY, Murrow R, Fröhlich F

Anesthesia-related changes in information transfer may be caused by reduction in local information generation.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Wollstadt P, Sellers KK, Hutt A, Frohlich F, Wibral M

Transcranial direct current stimulation (tDCS) of frontal cortex decreases performance on the WAIS-IV intelligence test.

Behavioural brain research

Sellers KK, Mellin JM, Lustenberger CM, Boyle MR, Lee WH, Peterchev AV, Fröhlich F

Awake vs. anesthetized: layer-specific sensory processing in visual cortex and functional connectivity between cortical areas.

Journal of neurophysiology

Sellers KK, Bennett DV, Hutt A, Williams JH, Fröhlich F

Targeting the neurophysiology of cognitive systems with transcranial alternating current stimulation.

Expert review of neurotherapeutics

Fröhlich F, Sellers KK, Cordle AL

Anesthesia differentially modulates spontaneous network dynamics by cortical area and layer.

Journal of neurophysiology

Sellers KK, Bennett DV, Hutt A, Fröhlich F

Transcranial alternating current stimulation modulates large-scale cortical network activity by network resonance.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Ali MM, Sellers KK, Fröhlich F